Premenstrual Dysphoric Disorder (PMDD) was first described in 1987, when it was included in the American Psychiatric Association’s DSM (Diagnostic Statistical Manual for mental health disorders)- although it was then called ‘Late Luteal Phase Dysphoric Disorder‘ . It refers to individuals who experience severe (life-affecting) irritability, anxiety, or low mood in the premenstrual phase (two weeks before menstruation), with symptoms disappearing between menstruation and ovulation .
PMDD is often described as ‘severe PMS’ (Premenstrual Syndrome) but this is NOT strictly true, since PMS is a term used to describe any symptom experienced in the premenstrual phase i.e. including physical symptoms such as constipation, migraine, painful breasts, or fatigue, and not only, or mainly, mood-related problems (which is the case for PMDD) .
PMDD is a highly controversial diagnosis because although it is a menstrual cycle-related issue by definition, it is classified as a mental health disorder . This is not the case for other hormone-related conditions that result in irritability, anxiety, or depression, e.g. thyroid disorders . So, this classification is felt by some to be another example of society’s habit of wrongly associating the female reproductive system with supposedly irrational thinking and behaviour .
However, this is not to say that experts do not agree that some people’s moods are significantly affected by their menstrual cycle, the disagreement is only around the way in which the problem is classified (e.g. is it a hormonal, reproductive health, or a psychiatric problem? Is there an underlying mental health disorder that is ‘triggered’ or ‘worsened’ by the menstrual cycle, or is it directly caused by the changing levels of sex hormones, external environment, something else, or a combination of these factors?), and treated (e.g. with anti-depressants/ psychological therapy, hormonal medications/ interventions, or lifestyle and dietary options)  .
Main symptoms: A diagnosis of PMDD requires the presence of at least five ‘PMS’ symptoms from the list below- with at least one of the main symptoms being severe irritability, depressed mood, or anxiety/ tension. These symptoms should only occur up to two weeks before menstruation and stop after menstruation begins. In order to meet the criteria for diagnosis, the symptoms should be tracked for at least two consecutive ovulation cycles in order to confirm the cyclical nature of symptoms. The symptoms should also be severe enough to significantly affect normal activities or relationships with others .
If your symptoms are severe and debilitating (i.e. they significantly limit your ability to work, socialise, or maintain personal relationships) it is likely that your doctor will prescribe some sort of medication.
Diagnosed PMDD is most commonly treated with SSRIs (Selective Serotonin Reuptake Inhibitors) which are a type of anti-depressant that has been found to be very effective in managing PMDD- but PMDD patients only need to take the medication for a few days before menstruation (up to a maximum of two weeks) .
Or, your doctor may prefer to prescribe a hormonal medication or device (usually the contraceptive pill, patch, or implant) to prevent symptoms by stopping ovulation from happening in the first place .
Non-medication approaches to managing PMDD:
The good news is that PMDD symptoms respond well to the four steps outlined on our ‘all symptoms‘ page, so it might be worth trying some of these options before turning to medication, or in combination with it:
Try a hormone-balancing diet– As outlined in this blog, a vegetable-based ‘anti-inflammatory’ diet can significantly improve all hormone-related symptoms.
We highlight additional advice for those suffering from PMDD, below;
Note: Vitex Agnus Castus is not suitable for those who are under 18; using hormonal medication (or devices); are pregnant, trying to conceive, or breast-feeding; or have a pituitary problem.
Regular exercise, particularly aerobic exercise, may help you combat stress and release tension. It also encourages your brain to release serotonin, which can improve your mood .
Research has shown that regular exercise, (more specifically cardio-respiratory fitness), and a healthy BMI (Body Mass Index), significantly reduces the risk of menstrual cycle-related health issues, including low mood .
Boost self-esteem- Low self-esteem has been found to increase the risk of developing the symptoms of depression, so it’s worth making sure that your self-esteem is OK, and if not, to do something about it .
Cognitive behavioural therapy (CBT) is one of the most effective treatments for low mood, and building self-esteem, and is available on the NHS. Research shows that the benefits of CBT may last longer than those of medication, although no single treatment is best for everyone. CBT helps you to understand how your problems, thoughts, feelings and behaviour affect each other. It can also help you to question your negative and anxious thoughts, to improve the way you see yourself, and reduce damaging internal thought processes. CBT usually involves meeting with a specially trained and accredited therapist for a one-hour session every week for 10-12 weeks.
Reduce stress hormones- Research shows that Mindfulness-based Cognitive Behavioural Therapy (MCBT) is highly effective in reducing menstrual cycle-related low mood, anxiety, and other symptoms  . Mindfulness works by focusing your awareness on the present moment and by acknowledging and accepting certain feelings. Being mindful can teach you how to overcome negative thoughts – for example, being able to challenge hopeless feelings.
This practice has been found to reduce ‘stress reactivity’, stopping the vicious cycle of low mood and anxiety constantly triggering the ‘fight or flight’ HPA (Hypothalamic Pituitary Adrenal) stress response- leading to further anxiety (and, therefore, worsening hormone-related symptoms) . MCBT usually involves meeting with a therapist for a one-hour session every week for three to four months.
If you have tried the suggested tips and tricks for at least 3 months, and your symptoms do not improve, please consult your doctor.
If you have any suggestions, or tips, for managing PMDD- please let us know– we can share them with others!
Page last reviewed and updated: June 2018
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